Greetings

Arcadi Navarro

Director of the Pasqual Maragall Foundation and the Barcelonaßeta Brain Research Center
Arcadi Navarro - Director of the Pasqual Maragall Foundation and the Barcelonaßeta Brain Research Center

Working tirelessly to advance. That’s exactly what we did in 2024—a year filled with hope for Alzheimer’s disease, marked by the European Medicines Agency’s (EMA) recommendation to approve the first drug in Europe capable of slowing its progression. This breakthrough marks a profound change in scientific research, as well as in the diagnosis and treatment of Alzheimer’s disease. It inspires us to strive for more—and better—science.

Sparked by this great step forward and the Foundation’s work thus far—we’ve achieved significant milestones throughout 2024. In the scientific field, we’ve made major strides in the early detection of the disease, paving the way for future strategies in prevention. We have developed cerebral organoids from stem cells—a research work that enables us to simulate the development of Alzheimer’s disease and study its onset and progression in greater depth. We have also demonstrated that blood flow decreases during the asymptomatic stages of Alzheimer’s. In addition, we’ve validated a new metric for measuring the accumulation of the beta amyloid protein in the brain, among other findings.

But we haven’t stopped there. We’ve actively participated in over 15 conferences throughout the year, including some of the world’s most prestigious events in the field, such as the Alzheimer’s Association International Conference (AAIC) and the Alzheimer’s & Parkinson’s Diseases Conference (AD/PDTM), among others. In research, we’ve also awarded our Pasqual Maragall Researchers Programme grants for the second year running. These grants, given to projects conducted at institutions outside our Foundation, support outstanding projects aimed at accelerating ground-breaking research in Alzheimer’s disease.

We are also proud to have launched a unique initiative in this regard, the HUB Alzheimer Barcelona, a collaborative project with Barcelona’s leading public hospitals and research centers specialising in Alzheimer's disease. This initiative expanded networking opportunities, fostered scientific excellence, attracted investment and enhanced the transfer of knowledge into clinical practice.

In the realm of institutional and social relationships, we have worked tirelessly to position Alzheimer’s disease as a priority on both policymaking and healthcare agendas. The report Proposals for a new prioritisation of Alzheimer’s disease in Spain, submitted to the Ministry of Health, was prepared with the collaboration of 30 scientific, health and social rights organisations. This report has been instrumental in shaping a model that promotes a holistic approach to Alzheimer’s and other neurodegenerative diseases.

We also continue to advocate for a change in the social perception of Alzheimer’s disease through awareness and prevention efforts. In this regard, we’d like to highlight the 50 talks on Alzheimer’s disease we’ve held across the region, the 7th edition of the Brain Film Fest –our film festival, which achieved again record attendance, as well as the related content across our blog and channels. And all this has been made possible while providing support to families of individuals affected by the disease through our online and in-person support programmes.

I invite you to read this report on the Foundation’s activities, made possible thanks to the collaboration of over 93,000 members, patrons, businesses, donors and study participants.

Every achievement detailed in these pages has been achieved through their support. They are the driving force behind our daily efforts, and their selfless commitment brings us closer to our goal: a world without Alzheimer’s disease.

2024

Alzheimer’s
today

Alzheimer's disease is the main cause of dementia, responsible for 60% to 70% of cases. It is estimated that in Spain there are more than 900,000 people suffering from Alzheimer's and other dementias, a figure that will double in the next twenty years.

900 Thousand <span class='nowrap'>people <sup>1</sup></span>suffer from Alzheimer's and other dementias.

900 Thousand people 1 suffer from Alzheimer's and other dementias.

2 out of 3 <span class='nowrap'>people <sup>2</sup></span>have or have had someone with Alzheimer's in their environment.

2 out of 3 people 2 have or have had someone with Alzheimer's in their environment.

80% of <span class='nowrap'>people <sup>3</sup></span>with Alzheimer's are cared for by family.

80% of people 3 with Alzheimer's are cared for by family.

1. Assessing the socioeconomic impact of Alzheimer’s in Western Europe and Canada (2017)

2. 5 Actitudes y percepciones de la población española sobre el Alzheimer, Fundación Pasqual Maragall (2020)

3. Coduras A, Rabasa I, Frank A, Bermejo-Pareja F, Lopez-Pousa S, Lopez-Arrieta JM, et al. Prospective one-year cost-of-illness study in a cohort of patients with dementia of Alzheimer's disease type in Spain: the ECO study. J Alzheimers Dis. 2010; https://pubmed.ncbi.nlm.nih.gov/20110605/

2024

Milestones
of the year

1 +info

The Foundation holds its seventh annual Brain Film Fest

The Foundation holds its seventh annual Brain Film Fest

The Brain Film Fest, held from 13 to 17 March 2024 at the CCCB in Barcelona, honoured Chilean director and producer Maite Alberdi with the Special Film Fest Award 2024. The festival, promoted by the Foundation, recognised Alberdi’s sensitive portrayal of ageing and brain-related issues through her empathetic and insightful filmmaking.

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1.6 million euros awarded to the winning projects of the second edition of the Pasqual Maragall Researchers Programme grants

1.6 million euros awarded to the winning projects of the second edition of the Pasqual Maragall Researchers Programme grants

Endowed with 1.6 million euros, the second call for proposals for the Pasqual Maragall Researchers Programme (PMRP) promotes excellence in Alzheimer's and other neurodegenerative disease research. The selected projects, led by Dr Silvia De Santis (CSIC-UMH) and Dr Alberto Rábano (CIEN), open new avenues to improve the diagnosis and understanding of these pathologies.

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The Foundation launches its new awareness campaign entitled “Coneix la recerca (Discover the research)

The Foundation launches its new awareness campaign entitled “<em>Coneix la recerca</em> (Discover the research)

This initiative, involving the posting of video interviews every two months during 2024, aims to educate the general public on the studies, projects and lines of research of the Barcelonaβeta Brain Research Center. This initiative brings scientific content to the public at large, offering it in an informative format in a language that is easy to understand for all types of audiences.

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Nearly 1,500 people attend lecture series “Recuerda” (Remember)

Nearly 1,500 people attend lecture series “<em>Recuerda</em>” (Remember)

Held online and welcoming nearly 1,500 participants, the fifth edition of the lecture series offered a scientific perspective on the impact of the disease on women and how people with Alzheimer's can be cognitively stimulated at home.

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We celebrate the tenth anniversary of the Alfa Study

We celebrate the tenth anniversary of the Alfa Study

Marking its tenth anniversary, the Alfa Study stands as one of the largest and most comprehensive cohorts, comprising nearly 2,700 participants. Over the past decade, it has achieved ground-breaking results in identifying Alzheimer's disease at its earliest stages and developing prevention programmes aimed at delaying or halting the onset of symptoms.

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Researchers conclude that a diet rich in omega-3 fats may be key to preventing Alzheimer's

Researchers conclude that a diet rich in omega-3 fats may be key to preventing Alzheimer's

In collaboration with the Hospital del Mar Research Institute, our research center, the BBRC, finds that the regular consumption of omega-3 rich foods, both from plant and marine sources, could be crucial in preventing Alzheimer's disease.

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Our research reveals how blood flow in the brain is reduced in asymptomatic stages of Alzheimer's

Our research reveals how blood flow in the brain is reduced in asymptomatic stages of Alzheimer's

As part of a multilateral collaborative project led by our research center (BBRC), we have been able to detect decreased blood flow in the brain during the early stages of the disease. This finding represents one of the principal conclusions of the study published in the journal Alzheimer’s & Dementia.

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We honour those individuals working daily to bring us closer to a world without this disease on World Alzheimer’s Day

We honour those individuals working daily to bring us closer to a world without this disease on World Alzheimer’s Day

Once again, this time with the initiative entitled “La recerca en Alzheimer té nom i cognom”, we commemorate this day by focusing on members of our research team who work daily to bring us closer to our mission: to live in a world without Alzheimer's.

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We create miniature brains from stem cells to explore the onset and progression of Alzheimer's

We create miniature brains from stem cells to explore the onset and progression of Alzheimer's

Our research center has created cerebral organoids that mimic the function of a real brain, also known as “mini-brains”, made from stem cells that allow researchers to simulate the development of the disease and explore in detail the factors that contribute to its onset and progression.

10 +info

We launch a new call for applications for the Ambassador Membership Programme

We launch a new call for applications for the Ambassador Membership Programme

The new Pasqual Maragall Foundation Ambassador Membership Programme offers our members the opportunity to participate directly in the day-to-day running of the organisation. Each year, select members can actively participate in various Foundation initiatives, including events, sports matches, and campaigns.

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We participate in prestigious conferences to gain new insights and promote our scientific research and activity

We participate in prestigious conferences to gain new insights and promote our scientific research and activity

With six talks and approximately twenty posters, the BBRC participates in AAIC 2024, the world’s most influential congress on scientific advancements in Alzheimer's and other dementias. This event brought together research teams from around the globe to share the latest developments in their research with the international scientific community.

12 +info

Third edition of the Diana Garrigosa Awards

Third edition of the Diana Garrigosa Awards

As part of the 7th Annual Meeting with our social base, held under the theme “La nova era de l’Alzheimer” (A new era in Alzheimer’s) and attended by more than 1,500 people, we present the third edition of the Diana Garrigosa Awards. This year, the awards honour the remarkable careers of Rosa Montero, journalist and writer, and Miguel Ríos, singer, both celebrated for their active and long-standing commitment to social values and rights.

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Launch of new Pasqual Maragall Foundation website

Launch of new Pasqual Maragall Foundation website

With a fresh new design, our revamped website is now more intuitive, modern and accessible to everyone. This update further serves to reflect our commitment to Alzheimer's research, as well as to those affected by the disease and their families.

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Introducing the Alzheimer Barcelona Hub

Introducing the Alzheimer Barcelona Hub

We launch the Alzheimer Barcelona Hub, a pioneering initiative driven by our commitment to advancing research and enhancing support for individuals and families affected by the disease. Backed by the Barcelona City Council, the Alzheimer Barcelona Hub brings together Hospital de Sant Pau, Hospital Clínic de Barcelona, Hospital del Mar and the Vall d'Hebron University Hospital, along with our research center, the BBRC, and the Ace Alzheimer Center Barcelona.

15 +info +info

We share our work

We share our work

As part of our meetings with political representatives to raise awareness and highlight the challenges facing Alzheimer's research, we welcomed Her Majesty the Queen Doña Sofía and the President of the Parliament of Catalonia, Anna Erra. During their visit, they toured our facilities to learn about our social and scientific work.

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We publish of a caregiver's guide for families affected by Alzheimer's

We publish of a caregiver's guide for families affected by Alzheimer's

In collaboration with the Barcelona Provincial Council, we have developed a new guide for family members taking care of individuals with Alzheimer's. This guide will address caregivers’ concerns, including understanding symptoms, providing care, managing change, navigating the grieving process, and ensuring legal protection, among other topics.

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Advocating for dementia to be a priority in public policy

Advocating for dementia to be a priority in public policy

On the occasion of the Parliament of Catalonia elections on 12 May, we are joining forces with the Ace Alzheimer Center, the Association of Relatives of People with Alzheimer's and Other Dementias of Barcelona (AFAB), the Alzheimer Catalonia Foundation and the Uszheimer Foundation to call for dementia to be prioritised in public policy, advocating for a National Agreement on Alzheimer's and Dementias.

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Strengthening our management team

Strengthening our management team

To support our ongoing expansion and adapt to the evolving social and research landscape, we are pleased to appoint Glòria Oliver as Deputy General Director following her tenure as Manager since the Foundation’s inception. Additionally, Dr Josep Maria Argimon, our current Director of Scientific Infrastructures, has been appointed Director of Relations with the Health System to further promote this key area.

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We confirm the Centiloid metric as a reliable tool for measuring amyloid plaques in Alzheimer's

We confirm the Centiloid metric as a reliable tool for measuring amyloid plaques in Alzheimer's

Building on research led by our research center and published in the journal Alzheimer's & Dementia, we have demonstrated the reliability of the Centiloid scale for quantifying amyloid plaques in the brain, a key hallmark of Alzheimer's disease.

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We present the report “Proposals for a new prioritization of Alzheimer's in Spain” to the Ministry of Health

We present the report “<em>Proposals for a new prioritization of Alzheimer's in Spain</em>” to the Ministry of Health

As part of the Alzheimer’s Observatory, an initiative led by our Foundation in collaboration with key organisations and experts from the scientific, health, and social sectors, we present this report to the Ministry of Health. It aims to advance a model for a comprehensive approach to Alzheimer's and other dementias.

21

Taking care of those who take care of us

Taking care of those who take care of us

We offer support to more than 300 individuals through our online and in-person support programmes for caregivers of relatives with Alzheimer's.

22

Spreading the word about Alzheimer's and its prevention

Spreading the word about Alzheimer's and its prevention

In 2024, we organised several informational conferences across the region to raise awareness about Alzheimer's disease and its prevention, while addressing any questions regarding this form of dementia and its broader context. This year, we have offered a total of 50 talks nationwide.

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We successfully conclude the campaign “The biggest lie about Alzheimer's” with excellent results

We successfully conclude the campaign “The biggest lie about Alzheimer's” with excellent results

The Foundation closes the “The Biggest Lie About Alzheimer's” campaign on a high note, raising €373,795 through charitable donations. The funds will support the Beta-AARC study at the Barcelonaßeta Brain Research Center (BBRC), which focuses on investigating biomarkers for the early detection of Alzheimer's disease.

In
detail

Budget

26143305

Budget

66% Pasqual Maragall Foundation 17177401

34% BBRC Research Center 8965903

Taula icona Arrow

Investment in Research in recent years.

Investment in Research in recent years.

MORE THAN75MEUR IN RESEARCH
2013 - 2024

15MEUR IN RESEARCH
2024

Revenue:26.143.305 €
Individuals
14.732.888 €
56%
Contributions from members and donors.
Companies and foundations
7.340.479 €
28%
Donations from companies and other foundations.
Public funds
3.095.490 €
12%
State and European subsidies for scientific or social impact projects.
Revenue from services
336.656 €
1%
We offer our state-of-the-art equipment and facilities to other organisations, reinvesting the revenue generated into our mission.
Financial income
637.790 €
3%
Expenses:26.056.628 €
Research programmes
15.408.661 €
59%
Pioneering research on the early detection and prevention of Alzheimer’s conducted at our research center, the BBRC. Through our research grants programme, we also support innovative projects across Spain.
Support for families, awareness initiatives and public advocacy
3.883.116 €
15%
Investment in caregiver support programmes, advocacy for public agenda change and raising awareness on the need for investment in Alzheimer's research, detection and prevention.
Investment in partner and donor network
5.623.645 €
22%
Programmes to expand membership in support of our cause through campaigns, events and other initiatives.
Administrative expenditures
1.103.671 €
4%
Investment to ensure the day-to-day operations and structure of the organisation.
Financial expenses
37.533 €

Aggregated data from the Pasqual Maragall Foundation and its research center, the Barcelonaßeta Brain Research Center (BBRC).

Provisional closure in 2024. Financial data subject to annual account audit.

We multiply your impact.

We multiply your impact.

For every euro invested in securing new partnerships, we generate a return of 3 euros.

244

Foundation
employees

Women Men

Women66% Women

Men34% Men

Pasqual Maragall Foundation employees

147

Foundation
employees

Women

67% Women

Women Men
Men

33% Men

Research Center
employees

97

Research Center
employees

Women

65% Women

Women Men
Men

35% Men

57 Published
articles
Published<br/>articles

Published in Q1 journals

84%

Published in D1 journals

63%
Ongoing studies
29 Ongoing studies
Clinical trials
3 Clinical trials
Samples processed
25.000 Samples processed
MRIs
942 MRIs
Study protocols
8 Study protocols
1.641 Sessions
Clinical sessions
956 Clinical sessions
Cognition sessions
881 Cognition sessions
Nursing sessions
818 Nursing sessions
Conferences attended
16 Conferences attended
Posters presented
35 Posters presented
Posters presented
25 Oral presentations
Therapy groups
In-person
therapy groups
Participating
caregivers
Online support programme
“Learn to take care and take
care of yourself”
Online
sessions
Participating
caregivers
“Learn to take care and take
care of yourself” meetings
Meetings
Participating
caregivers
2Social research
studies
13Projects submitted to
private calls and board of patrons
7Projects submitted
to public calls
15Visual materials
and infographics
1 Guide "Psychological and behavioral symptoms of Alzheimer's: understanding them and learning to manage them", funded by the Barcelona Provincial Council Guide
1,9M Visits to the blog
“Let's talk about Alzheimer's“
22 New articles
3 New help guides
50 Educational talks
4.516 Brain Film Fest attendees
Media and communications
34 Press releases
89 New published
in the website
1.896 Media appearances
640.661.300 Total media
audience
11.500.324€ Advertising
value equivalent
Social media
1.472 Social media
posts
12.711.912 Impressions
128.821 Followers
Members
93.554 Members
New members
18.574 New members
14.732.888 € Members contribution
Donations
6.285 Donations
416.786,40 € Donors contribution
Companies on the patronage council
15 Companies on the patronage council
580.200 € Patronage council contribution
Solidarity <br/>initiatives
491 Solidarity
initiatives
186 Solidarity
celebrations
652 Unforgettable
shops
247 Unforgettable
pharmacies
210.000 € Solidarity initiatives contribution
18.507,36 € Marina WalkTrail contribution
Bequests
25 Bequests
853.551,86 € Bequests
contribution
691 Individuals expressing
interest in bequests
Telephone<br/>conversations
392,988 Telephone
conversations
418,500 Face to face
conversations

Research

To work towards a future without Alzheimer's, we need to conduct research that is rigorous, innovative and collaborative. In 2024, the Barcelonaßeta Brain Research Center made significant progress in understanding and preventing Alzheimer's. By focusing on prevention and analysing cognitive functions in both healthy and pathological ageing, we have continued to advance our knowledge of the biological processes of this disease. Our four collaborative research groups and four technology platforms have established new methodologies that enhance early detection and accelerate Alzheimer's research.

Research
Groups

Research
facilities

International
consortia

International consortia

PROMINENT

The BBRC is part of the PROMINENT consortium, a public-private collaboration, funded by the Innovative Health Initiative for a period of five years, which brings together experts in neurodegenerative diseases and clinical neuroscience, artificial intelligence, health economics and patient advocacy.

The project partners also include some of Europe's leading medical centers for the diagnosis and treatment of cognitive disorders.

AD-RIDDLE

The AD-RIDDLE consortium brings together public and private leaders from across Europe to transform Alzheimer’s prevention and treatment, equipping healthcare professionals with advanced tools for accurate detection and diagnosis.

Over five years, the project will develop a modular platform featuring a suite of tools to support every stage of the clinical pathway. This includes a digital community engagement portal, advanced screening tools for more accurate risk detection and early diagnosis, a decision-support toolkit for healthcare providers, and therapies tailored to each patient.

SpeechDx

The Alzheimer's Drug Discovery Foundation (ADDF) SpeechDx longitudinal study is the first to create the largest repository of speech and voice data to help accelerate the detection, diagnosis and monitoring of Alzheimer's disease through these biomarkers.

The recorded voice samples from the study will be combined with clinical and biomarker data to develop algorithms for the creation of new speech biomarkers. The study will last three years and will collect data from 2,650 participants from five different centers, including the BBRC, which will contribute 400 people from the Alfa+ and Beta-AARC cohorts.

COMMUTE

The COMMUTE project investigates the risk of dementia and neurodegeneration following coronavirus infection. The study will examine the underlying mechanisms connecting COVID-19 infections to neurodegenerative diseases.

Funded by the European Union, the project brings together 11 partners across Europe. It integrates computational and biological research methods, using artificial intelligence to analyse patient data and evaluate whether COVID-19 infection increases the risk of neurodegenerative diseases.

EU-FINGERS

The BBRC is partner and leader of one of the work packages of the “EUROFINGERS” project: multimodal precision prevention toolbox for dementia in Alzheimer's disease.

This initiative aims to generate prevention tools for Alzheimer's disease and other dementias, and seeks to provide a common framework for multimodal studies on the prevention of dementia due to Alzheimer’s disease.

In the context of this project, a BBRC study participant is part of the EU-FINGERS advisory committee to provide advice and recommendations to researchers and enrich the research with a diversity of voices and perspectives.

Main
research studies

Main research studies

Alfa Study

The Alfa study is a key research platform for understanding the pathophysiology of Alzheimer's in its preclinical phase and advancing the development of preventive treatments. Launched in 2013 by the “la Caixa” Foundation, it is one of the most ambitious research initiatives in the world, involving 2,743 participants aged 45 and 75, the majority of whom are descendants of individuals with Alzheimer's.

The Alfa study represents a strategic infrastructure enabling further research into early detection and identification of risk factors for the disease. It also provides essential data for most BBRC studies and serves as a basis for clinical trials focused on Alzheimer's prevention, thanks to the detailed characterisation of its Alpha participants.

Fundacio La Caixa

2.743 People between the
ages of 45 and 75

HeBe

The aim of HeBe is to identify blood factors that have a rejuvenating or aging effect on the human brain.

The results will improve the diagnosis of Alzheimer's disease or other neurodegenerative diseases in their earliest stages. They will also be useful for detecting people more susceptible to developing these diseases, predicting their prognosis, monitoring their progression and the effectiveness of a possible treatment.

This project receives funding from the European Research Council (ERC) within the framework of the European Union's Horizon 2020 research and innovation programme (grant agreement no. 948677).

ERC - European Research Council

Alfa+

Alfa+ is a cohort, prospective and observational study that aims to describe the biological processes and identify factors that can predict the preclinical phase of Alzheimer's disease.

Thanks to the extensive characterization of 420 participants without cognitive impairment from the Alfa study, the Alfa+ analyses the association between biological, structural, functional and neurocognitive brain markers that characterise the preclinical phase of the disease and describe its natural history. It is supported by the Adey Foundation and the Sabadell Foundation.

Fundación Adey Fundació Sabadell

PROAD

The PROAD project aims to identify proteomic profiles in blood that can predict cognitive decline in cognitively healthy people with an increased risk of developing Alzheimer's.

With this study, in which plasma samples from the Alfa+ cohort will be analysed, the BBRC team hopes to be able to find new prognostic biomarkers in the preclinical phase of the disease.

AlfaSleep

The aim of the AlfaSleep project is to characterise sleep patterns with subjective and objective measures in middle-aged adults without cognitive impairment and with an increased risk of developing Alzheimer's in the future, and relate them to biomarkers and state-of-the-art neuroimaging data.

Thanks to its multimodal approach and the study participant cohort, enriched by risk factors, the project will contribute to the understanding of the mechanisms underlying the association between sleep and cognitive impairment.

Thus, the project aims to develop non-invasive biomarkers and preventive strategies aimed at sleep. AlfaSleep has the participation of 200 people from the Alfa+ cohort.

NeuroCOVID

This study, funded by La Marató de TV3 Foundation and lasting three years, investigates the neurological effects of Covid-19 in people with different risks of developing Alzheimer's.

To this end, the researchers use mini-brains as an analytical and predictive model, customised organoids of human brains, from participants of the Alfa cohort, and subjected to different traumas, including SARS-Cov2 infection.

PROSPECT-AD

Speech impairments are a feature of the early stages of Alzheimer's disease and, consequently, the analysis of speech performance is a promising new digital biomarker for the detection of the disease.

The aim of PROSPECT-AD is to validate speech biomarkers for the identification of individuals with early signs of Alzheimer's and monitor them longitudinally.

In addition, digital biomarkers of language and speech open the door to screening methods for populations at greater risk of suffering the disease at very early stages, necessary for future clinical trials on Alzheimer's disease modifying drugs. PROSPECT-AD collects data from participants from European cohorts , 100 of them from the BBRC Beta-AARC study.

Beta-AARC

The project 'Beta-AARC: Cohort study for the identification of blood biomarkers in the population with subjective cognitive decline', underway from 2021, deepens the knowledge of the factors that influence the onset of Alzheimer's disease and the detection of biomarkers to identify people at increased risk of developing the disease before the first symptoms appear.

It is a cohort study that will include approximately 200 people aged between 55 and 80 who experience a subjective deterioration of memory or other cognitive abilities, such as attention, planning ability and orientation.

The Beta-AARC study is supported by ACS Foundation, Ramón Areces Foundation and the Naccari Ravà Foundation.

Fundación ACS Fundacion Ramón Areces Fundació Naccari Rava

SCAP-AD

The SCAP-AD project aims to validate new ultrasensitive diagnostic methods for the early detection of Alzheimer's disease. Led by the CIEN Foundation and with the participation of the Barcelonaβeta Brain Research Center (BBRC), this project seeks to apply precision medicine to improve the diagnosis and treatment of neurodegenerative diseases such as Alzheimer's.

The BBRC is responsible for coordinating the neuroimaging work of participating centers, overseeing the collection and archiving of magnetic resonance images from each site, and ensuring high-quality image processing and quality control.

The study will establish two large population cohorts: A digital cohort to explore the use of an online cognitive assessment test via a web platform and a large clinical validation cohort.

Financiado por la Unión Europea - NextGenerationEU Plan de Recuperación, Transformación y Resiliencia

Gobierno de España - Ministero de ciencia e innovación Insituto de Salud Carlos III Fundación Centro Investigación Enfermedades Neurológicas

Clinical
trials

Clinical trials

AHEAD A3-45

The BBRC is one of the centers selected to participate in the AHEAD trial. The study plans to gather 1,400 participants from around the world to evaluate the efficacy and safety of a monoclonal antibody directed against the beta-amyloid protein, lecanemab, to prevent Alzheimer's disease in people aged 55 to 80 with high risk of developing it.

The selected participants will undergo the tests described in the trial protocol at the BBRC facilities, such as neuropsychological tests, or MRIs among others. The drug will also be administered to the people that meet all the requirements.

Elecsys Amyloid Plasma Panel

Elecsys Amyloid Plasma Panel (EAPP) is a multicenter, prospective and non-interventional study with the aim of demonstrating the clinical performance of the EAPP test, a test to facilitate the early diagnosis of Alzheimer's.

This tool would identify the likelihood of amyloid pathology in people with subjective memory complaints from a blood test, and determine whether they should undergo further evaluations and tests that could confirm the diagnosis. In this clinical trial will participate people aged between 55 and 80 with subjective memory complaints or mild cognitive impairment.

Scholarships
and grants

Research contract, Ramón y Cajal programme

Lead Researcher (LR): Dr Marta del Campo

Funded by: Spanish Research Agency (AEI) – Ministry of Science, Innovation and Universities

Project Number: RYC2023-043831-I, funded by MCIN/AEI/10.13039/501100011033 and by the ESF+

ALPHA+EBRAINS: Integrating the ALFA+ cohort study into EBRAINS for Neurodegenerative Research

LR: Xavier Serra Picamal (Data Center)

Funded by: EBRAINS Open Calls

Project Number: ALFA+EBRAINS project, financed by the EBRAINS Open Call “Recruiting large data collections for FAIR data sharing and analysis in EBRAINS”

CoPATH-AD: Understanding the effect of multiple co-pathologies on AD pathophysiology

LR: Dra. Marta del Campo

Funded by: Spanish Research Agency (AEI) – Ministry of Science, Innovation and Universities

Project Number: PID2023-153312OB-I00, funded by MCIN/AEI/10.13039/501100011033 and by ERDF, EU

DETEC-PK: Detection of Aggregated TDP43 in CSF and Plasma via Proteinase K

LR: Dra. Marta del Campo

Funded by: CaixaResearch Institute – Innovation Hub Fund

Project Number: DETEC-PK project, funded by the CaixaResearch Institute in the second call for proposals of the Innovation HUB Fund

Establishing a personalised cerebral health service for dementia risk stratification and prevention: The B-HEALTH Project

LR: Dr. Oriol Grau-Rivera

Funded by: PI24/00116, funded by the Carlos III Health Institute (ISCIII) and ERDF, EU

Project Number: Project Number: PI24/00116, funded by the Carlos III Health Institute (ISCIII) and ERDF, EU.
Project managed by IMIM (Hospital del Mar Research Institute)

Support programmes

Alzheimer's is a disease that affects not only those diagnosed, but also everyone around them. Therefore, in 2024, we have continued our mission to support those caring for family members with Alzheimer's through group support and training programmes, both in-person and online.

The in-person group therapy programme has established 5 new groups, involving a total of 40 caregivers.

The programme has received a grant awarded by the Department of Social Rights of the Generalitat de Catalunya and funding from Barcelona City Council.

Currently, 1,653 people have participated in the 177 groups organised since the initiative was launched in 2013 throughout Spain.

The online support programme “Learn to take care and take care of yourself“ has conducted 31 groups, with 287 participants.

The programme has received a grant from the Department of Health of the Generalitat de Catalunya and also the support of Barcelona City Council and the Ministry of Social Rights, Consumption and Agenda 2030 of the Spanish Government. Also the support of Santalucía Seguros, Aigües de Barcelona, Libra and the M. Teresa Rodó Foundation (FMTR).

Since 2021, the year in which the psychoeducational programme began, we have accompanied 770 caregivers in the 88 organised groups.

Government of Catalonia Government of Catalonia Ajuntament de Barcelona Ministerio de derechos sociales, consumo y agenda 2030 Aigües de Barcelona FMTR Libra - Gestión de proyectos Seguros Santaluciía

1.653 people have participated in the 177 groups

769 caregivers in the 88 organised groups

You make it
possible

Collaborators

Strategic patron
Fundacio La Caixa
Major patrons
Allianz Fundacion Ramón Areces Ajuntament de Barcelona Diputació de Barcelona Fundación ACS Endesa
Patrons
Moventia Fundació Sabadell Libra - Gestión de proyectos HAM
Associated companies
Eurofragance Aigües de Barcelona Fiatc Vopi4
Institutional support
Government of Catalonia Unió Europea - Fons Europeu de Desenvolupament Regional
Fundación Adey Seguros Santaluciía Fundació Naccari Rava Fundación María Francisca de Roviralta FMTR Fundación Susana Monsma HM Hospiales Bonpreu

Ineco

RTVE

Alzamora Carton Packaging

Cirsa Servicios Corporativos

Inmo Bosmer, S.L.

Fundació Antoni Serra Santamans

Institute of Knowledment and Ketworking SLU

Caprabo

Janssen

Lilly

Roche Diagnostics

Lund University

University of Amsterdam

Universitat de Barcelona

Universitat Oberta de Catalunya

CNIC

IRSI Caixa

VUMC

Altoida

KIElements

F. Hoffmann-La Roche Ltd

IDIBAPS

Karolinska Institutet

Combinostics

Hospitaux de Bordeaux

UKC Ljubljana

University of Eastern Finland

IHE. The Swedish Institute for Health Economics

Bioartic

Uniklinik Cologne

Figers Brain Health Institute

University of Gothenburg

Maastricht University

University of Leicester

Imperial College London

Alzheimer Europe

University of Perugia

Davos Alzheimer's Collaborative

Fujeribio

Sanofi

C2N Diagnostics

Neotiv

Fraunhofer-Gesellschaft

University of Luxembourg

University of Copenhaguen

Barcelona Supercomputing Center

University of Vienna

Kairntech

Luxembourg Institute of Health

Shops

Companies, entities and professionals who are strategic collaborators in 2024

  • A.G.S. de Jerez, Costa Noroeste y Sierra de Cádiz
  • Acadèmiadel Cinema Català
  • Ace Alzheimer Center Barcelona
  • Adif Estaciones Barcelona
  • Agbar
  • Agència Catalana de Cooperació al Desenvolupament
  • Ajuntament d'hospitale tde Llobregat
  • Ajuntament d'igualada
  • Ajuntament de Barcelona
  • Ajuntament de Caldes de Montbuí
  • Ajuntament de Calella
  • Ajuntament de Castelldefels
  • Ajuntament de Gavà
  • Ajuntament de Girona
  • Ajuntament de Granollers
  • Ajuntament de Lleida
  • Ajuntament de Manresa
  • Ajuntament de Mollet Del Vallès
  • Ajuntament de Palamós
  • Ajuntament de Reus
  • Ajuntament de Sabadell
  • Ajuntament de Sant Celoni
  • Ajuntament de Sant Cugat
  • Ajuntament de Sant Feliu de Llobregat
  • Ajuntament de Sant Joan Despí
  • Ajuntament de Tarragona
  • Ajuntament de Terrasa
  • Ajuntament de Vilafranca del Penedès
  • Ajuntament de Vilanova i la Geltrú
  • Ajuntament del Vendrell
  • Alcampo
  • Alcampo Sant Adrià
  • Alcampo Sant Boi
  • Alcampo Sant Quirze
  • Alzheimer Catalunya Fundació
  • Alzheimer Europe
  • Área de Gestión Sanitaria Sur de Córdoba
  • Área Sanitaria da Coruña
  • Associació de Familiars d'Alzheimer de Barcelona
  • Ayuntamiento de Barbastro
  • Ayuntamiento de Huesca
  • Ayuntamiento de Jaca
  • Ayuntamiento de Logroño
  • Ayuntamiento de Teruel
  • Ayuntamiento de Zaragoza
  • Betevé
  • Blanquerna. Comunicació i Relacions Internacionals
  • CAP Igualada
  • CAP Les Hortes
  • CAP Muralles de Tarragona
  • CAP Palamós
  • CAP Roger de Flor
  • Carrefour
  • Carrefour Cabrera
  • Carrefour Girona
  • Carrefour Igualada
  • Carrefour Montigalá
  • Catalunya Film Festivals
  • Cbre - Kudos
  • CC Berceo
  • CC Bonaire
  • CC El Osito
  • CC El Rosal
  • CC Gran Turia
  • CC La Loma
  • CC Lagoh
  • CC MN4
  • CC Nueva Condomina
  • CC Odeon
  • CC Parque Rioja
  • CC Principe Pio
  • CC Puerto Venecia
  • CC Puerto Venecia
  • CC Salesas
  • CCValle Real
  • Ce C/Alboraya
  • Centre de Cultura Contemporània de Barcelona (CCCB)
  • Centro de Estudios Gregorio Marañón
  • Centro de Referencia Estatal de Atención a Personas con Enfermedad de Alzheimer y Otras Demencias del Imserso
  • Centro de Salud Cuenca III
  • Centro Doctor San Martin
  • Centro Internacional Sobre el Envejecimiento
  • Cita Alzheimer
  • Clinica Quirón
  • Cm Conde Duque
  • Cm Reina Victoria
  • Complejo Hospitalario Universitario de Canarias
  • Confederación Española de Alzheimer
  • Confederación Española de Familiares de Alzheimer (CEAFA)
  • Confederación Española de Organizaciones de Mayores
  • Consejo Español del Cerebro
  • Consejo General de Colegios Oficiales de Psicólogos
  • Consejo General de Enfermería
  • Cre Alzheimer
  • Creu Roja Santa Coloma de Farners
  • Cruz Roja España
  • Centro de Salud Albarizas
  • Centro de Salud Alcacer
  • Centro de Salud Barrio Bajo
  • Centro de Salud Bembibre
  • Centro de Salud Bétera
  • Centro de Salud Campanar
  • Centro de Salud Cañada
  • Centro de Salud Casines
  • Cs Catarroja
  • Centro de Salud de Asistencial Este
  • Centro de Salud El Limonar
  • Centro de Salud Eliana
  • Centro de Salud Federico Rubio
  • Centro de Salud Filiberto Villalobos
  • Centro de Salud Fuente de San Luis
  • Centro de Salud Garrido Norte
  • Centre de Salut Godella
  • Centre de Salut Guillem de Castro
  • Centro de Salud Huelva
  • Centro de Salud La Granja Dr Manuel Blanco
  • Centro de Salud La Milagrosa
  • Centro de Salud La Plasencia
  • Centro de Salud Las Delicias
  • Centro de Salud Leganitos
  • Centro de Salud Liria
  • Centro de Salud Loriguilla
  • Centro de Salud Los Gallos
  • Centro de Salud Los Marqueses
  • Centro de Salud Madre De Dios
  • Centro de Salud Malilla
  • Centro de Salud Manises
  • Centre de SalutMassanassa
  • Centro de Salud Miguel Armijo
  • Centro de Salud Miguel Servet
  • Centro de Salud Montealegre
  • Centre de Salut Nou Moles
  • Centro de Salud Paiporta
  • Centro de Salud Peñarroya
  • Centro de Salud Plaza Segovia
  • Centro de Salud Ponferrada I
  • Centro de Salud Ponferrada II (Picotuerto)
  • Centro de Salud Ponferrada IV
  • Centro de Salud Puerta de la Villa
  • Centre de Salut Quart de Poblet
  • Centre de Salut Ribarroja
  • Centre de Salut Rocafort
  • Centro de Salud Rodriguez Arias
  • Centro de Salud Ronda Norte
  • Centro de Salud Ronda Sur
  • Centro de Salud Rota
  • Centro de Salud Salamanca
  • Centro de Salud San Andrés Torcal
  • Centro de Salud San Benito
  • Centro de Salud San Isidro
  • Centro de Salud San Juan
  • Centro de Salud Santa Colonia De Inés
  • Centro de Salud Santa Marta
  • Centro de Salud Serrana
  • Centro de Salud Sur
  • Centro de Salud Tiro Pichon
  • Centro de Salud Torrelavega
  • Centro de Salud Torrente I y II
  • Centro de Salud Trafalgar
  • Centre de Salut Tres Forques
  • Centre de Salut Trinitat
  • Centro de Salud Villafranca Del Bierzo
  • Centre de Salut Xirivella
  • Departament de Cultura (Generalitat de Catalunya)
  • Departament de Drets Socials (Generalitat de Catalunya)
  • Departament De Salut (Generalitat De Catalunya)
  • Diputació De Barcelona
  • El Corte Inglés
  • El Corte Ingles Ademuz
  • El Corte Ingles Avenida de Francia
  • El Corte Inglés Nuevo Centro
  • Fiatc
  • Fundació Catalunya La Pedrera
  • Fundació d'Atenció a La Dependència Sant Joan de Déu
  • Fundació Hospital de l’Esperit Sant
  • Fundació Uszheimer
  • Fundación Adey
  • Fundación Antoni Serra Santamans
  • Fundación Cien
  • Fundación Edad y Vida
  • Fundación Eguía Careaga
  • Fundación Española Para la Ciencia y la Tecnología
  • Fundación Helpage International España
  • Fundación María Teresa Rodó
  • Fundación Pilares
  • Gerencia de Atención Integrada de Valdepeñas
  • Gerencia de Atención Integrada Manzanares
  • Grupo Libra GP
  • Grupo Social Lares
  • HM Hospitales
  • Hospital Alto Guadalquivir
  • Hospital Arnau de Vilanova de Valencia
  • Hospital Bierzo
  • Hospital Cabueñes
  • Hospital Carlos III
  • Hospital Clínico San Cecilio
  • Hospital Clínico Universitario Virgen se la Arrixaca
  • Hospital Collado Villalba
  • Hospital Costa Del Sol
  • Hospital d'igualada
  • Hospital de Cuenca
  • Hospital de Lleida
  • Hospital de Manises
  • Hospital de Palamós
  • Hospital de Ronda
  • Hospital de Sagunto
  • Hospital de Sant Celoni
  • Hospital de Tarancon
  • Hospital del Mar
  • Hospital del Sur
  • Hospital Fuenlabrada
  • Hospital General de Valencia
  • Hospital Insular
  • Hospital Jove
  • Hospital La Fe
  • Hospital La Luz
  • Hospital La Plasencia
  • Hospital Liria
  • Hospital Manacor
  • Hospital Materno
  • Hospital Puerta de Hierro Majadahonda
  • Hospital Puerto Real
  • Hospital Ribera Juan Cardona
  • Hospital San Eloy
  • Hospital San Juan de la Cruz
  • Hospital San Rafael
  • Hospital Sanitas la Moraleja
  • Hospital Santa Elena
  • Hospital Sierrallana
  • Hospital Son Espases
  • Hospital Torrejon
  • Hospital Txagorritxu
  • Hospital Úbeda
  • Hospital Universitari Arnau de Vilanova
  • Hospital Universitari Sant Joan de Reus
  • Hospital Universitari Santa Maria de Lleida
  • Hospital Universitario Clínico San Cecilio
  • Hospital Universitario de Gran Canaria Doctor Negrín
  • Hospital Universitario de la Ribera
  • Hospital Universitario General de Villalba
  • Hospital Universitario Rey Juan Carlos
  • Hospital Universitario Torrecárdenas
  • Hospital Valle del Guadiato
  • Hospital Virgen de las Nieves
  • Hospital Virgen del Valme
  • Hospital Virgen Vega
  • Hospital Zumarraga
  • HR Sanchinarro
  • Institut Català de les Empreses Culturals
  • Institut de Neurociències i Universitat De Barcelona
  • Instituto de Neurociencias de la Universidad de Barcelona
  • Institutose Neurociencias UMH-CSIC
  • Instituto de Salud Carlos III
  • Instituto de Salud Global Barcelona
  • Instituto Matia
  • Johnson & Johnson’s (Premio Afectivo Efectivo)
  • Leroy Merlin
  • Lidl
  • Mercadona
  • Miguel Ríos Campaña
  • Minimal Films
  • Ministerio se Derechos Sociales, Consumo y Agenda 2030 (Gobierno de España)
  • Mirasol Centre
  • Neuroestany
  • Obramat Burgos
  • Organización Sanitaria Integrada Araba
  • Parc Sanitari Sant Joan de Déu
  • Plataforma de Mayores y Pensionistas
  • Quiron
  • Residencia La Candelaria
  • Residència La Torreta
  • Rosa Montero Gayo
  • Rtve Catalunya
  • Sanitas Hospitales
  • Santalucía Seguros
  • Selecta Play
  • Servei d'Orientació i Acompanyament a Famílies
  • Sociedad Española de Enfermería Neurológica
  • Sociedad Española de Geriatría y Gerontología
  • Sociedad Española de Medicina de Familia y Comunitaria
  • Sociedad Española de Médicos de Atención Primaria
  • Solidaridad Enfermera
  • Som Multiespai
  • Suara Cooperativa
  • Supermercado Día
  • TV3
  • UAC Distrito Bahía de Cádiz
  • Unión Democrática de Pensionistas y Jubilados de España
  • Vithas

Members

Thank you for making it possible!

In 2024, your solidarity and commitment have grown stronger than ever. Over 18,000 people, organisations and companies have joined our project to help create a future where everyone can hold onto their memories.

Thanks to your support, we can continue advancing research and supporting people living with Alzheimer's. You are part of the solution, and with your strength, we move closer each day to a future without this disease.

Once again, individuals and organisations from across the country have dedicated their creativity to this important cause. Your initiatives and ideas have made a lasting impact and propelled our mission.

Thank you for being there and for standing by our side, now and always.

Evolution of the number of members

Evolution of the number of members
Evolution of the number of members
93.554 Members

Companies and individuals
in solidarity

Rounding up for early detection

Year after year, more and more businesses choose charity rounding up—a powerful initiative that generates a triple positive impact: bolstering the fight against Alzheimer's, fostering a spirit of solidarity, and communicating the company’s core values to its community.

Susanna Juan

“Our experience has been very positive and professional. Following each campaign, we normally visit the recipient organisations, where they share with us the specific projects that benefit from the donations. Our visit to the Pasqual Maragall Foundation was particularly memorable, not only for the warm welcome we received but also for the chance to gain first-hand knowledge into their research on Alzheimer’s disease and the support they provide to family caregivers.”

Susanna Juan

CSR Manager at Bonpreu i Esclat

Unforgettable businesses and pharmacies

In 2024, 652 businesses and 247 pharmacies joined the Pasqual Maragall Foundation in the fight against Alzheimer's. Bakeries, hairdressers, pharmacies and cafés came together to help us create a future where everyone can remember, becoming unforgettable allies in this mission.

Marina Rubio

“At Recuperation, one of our core objectives is to collaborate with projects and initiatives that promote solidarity. This year, we decided to join forces with the Pasqual Maragall Foundation in the fight against Alzheimer’s disease. We are proud to be a part of this initiative, because we firmly believe in the importance of its work in advancing prevention, diagnosis and treatment of this disease, which has a profound and growing impact on society.”

Marina Rubio

From Recuperat-ion.com, joining us in the commitment against Alzheimer's

Solidarity initiatives

The year 2024 saw significant strides in Alzheimer’s research, bringing us even closer to a future without this disease. Thanks to the 491 initiatives promoted by our partners, we raised more than €210,000 to ensure continued research.

Our second consecutive year with the Marina WalkTrail

In 2024, the Nordic pole walking event, co-organised by the Amics de l’Hospital del Mar Foundation and the Pasqual Maragall Foundation raised €18,507. This donation represents a vital boost for the collaborative research project between the BBRC and the Hospital del Mar Institute for Medical Research (IMIM).

Our second consecutive year with the Marina WalkTrail

“At the Amics de l'Hospital del Mar Foundation, we believe in the power of solidarity, health and sport as catalysts for change. The Marina WalkTrail, a Nordic walking route, was created to inspire healthy habits through physical activity while fostering emotional well-being and promoting values such as philanthropy, camaraderie, friendship, and the shared commitment of walking together for a cause. This initiative unites efforts to promote biomedical research at Hospital del Mar and supports the fight against diseases such as Alzheimer's. It demonstrates that physical activity and solidarity can work hand in hand to drive progress in medicine.”

Maribel Pérez i Piñero

Director of the Amics de l’Hospital del Mar Foundation

Books that inspire - Leve Atardecer: Cuando solo nos quede el amor (Gentle Sunset: When all we have left is love)

This book was born from the co-author Dolores’ desire to share her personal journey as she cared for her husband during his struggle with Alzheimer's disease. Along with her friend María Jesús Mañas, they have crafted a book that brings together practical advice and poetry, offering both solace and everyday solutions to families dealing with similar life challenges. The book was a family endeavour, featuring cover art by her daughter and the support of her sons throughout the process.

<strong>Books that inspire</strong> - <em>Leve Atardecer: Cuando solo nos quede el amor</em> (Gentle Sunset: When all we have left is love)

“We chose to transfer our copyrights to the Pasqual Maragall Foundation, in support of its research in the fight against this devastating disease. My family, along with my friend and co-author, agreed to make this modest contribution. For 15 years, my husband has been on a journey into the mists of forgetfulness, his memory of names and faces slowly fading. Yet I walk beside him joyfully, as I still remember his name.”

Dolores Vendrell

Co-author of the book.

Solidarity events

In 2024, solidarity became the hallmark of numerous special occasions, culminating in 186 solidarity events. These events not only promoted our social and scientific initiatives but also raised €68,279.

Ricardo & Blanca

“When planning our wedding, we were clear about not wanting to give our guests wedding favours that might be forgotten. Our lives have been marked by Alzheimer's, as two of our grandparents died from this disease. Their unconditional support inspired us to contribute our grain of sand to this cause. Our guests were touched by the magnets and the postcards we shared, which carried a meaningful message.”

Ricardo & Blanca

unforgettable couple

Solidarity wills

In 2024, 25 people formalised their solidarity wills, while 691 others expressed interest in leaving a legacy of hope—a future free from Alzheimer's, where no family has to endure the devastating impact of this disease. Thanks to their generosity, the Pasqual Maragall Foundation has received more than €850,000 in 2024.

Testimonial

Juana and Carmen Polo Ferrer, two women who are no longer with us, yet their legacy continues to support ongoing research. Their memory and commitment will live forever in the fight against Alzheimer's.

“My dear aunts, Carmen and Juana Polo Ferrer, epitomised generosity—a trait seemingly woven into the very fabric of their being. This found its ultimate expression in their solidarity will. They chose the Pasqual Maragall Foundation as the beneficiary of their legacy, as they were convinced that their contribution would really serve to advance research towards a cure for Alzheimer's. Their decision was rooted in the Foundation's demonstrated commitment, integrity, solvency and proven track record of solidarity. They were confident that their legacy would be instrumental in shaping a brighter future for those affected by this disease.”

Pilar Polo